A virtual event dedicated to transcatheter treatment strategies for coronary and structural heart disease

Overview

Radcliffe Cardiology is delighted to announce that Transcatheter Interventions Online (TIO) will return on 9–12 April 2025.

Over five hugely successful years, TIO has established itself as a leading virtual event serving the educational needs of the global interventional cardiology community.

Under the guidance of Course Director, Prof Nicolas Van Mieghem (Erasmus MC, Rotterdam, NL), TIO brings together a faculty of international renown, case centres of excellence and a global audience of thousands of HCPs, for education that is both authoritative and enduring in support of superior patient outcomes.

With a mix of live cases, practical tips and tricks, insightful presentations and debate, this CME-accredited event will again be carefully curated to enhance knowledge, address practical challenges and explore innovative solutions in real-world settings.

Due to demand from our attendees, this year’s programme has been extended to four days. The first three days will maintain a global outlook, with faculty and case centres selected to represent and resonate with our truly international audience. The new fourth day will be TIO 2025 I US Focus – dedicated to the challenges of US-based practice.

With a reach that is truly global – in 2024, over 2,500 healthcare professionals from 155 countries joined for CME-accredited best-in-class education – TIO 2025 promises to be larger still.

Whatever your geographical location of practice, TIO 2025 is here to support your endeavour to achieve optimum outcomes in clinical practice.

Register now to join thousands of HCPs worldwide at TIO 2025.

Join the conversation - #TIOCongress2025

*Transcatheter Interventions Online 2025's programme will be submitted to the European Board for Accreditation of Continuing Education for Health Professionals (EBAC) for 11 CME points, equating to 11 hours of effective education time. Physicians may convert EBAC External CME credits to AMA PRA Category 1 Credits™.

Programme

(Please note this programme is subject to change)

Day 1 - Structural Heart Disease


Day One Welcome


Optimising Large-Bore Venous Closure: PerQseal® Elite in Real-World Practice

Breakout

Chair: Vasileios Panoulas, London, UK

Panel: Rutger-Jan Nuis, Rotterdam, NL; Mohamed Abdel-Wahab, Leipzig, DE

  • Introduction and Session Objectives – Vasileios Panoulas

  • The Evolving Landscape of Large-Bore Venous Closure – Vasileios Panoulas

  • PerQseal® Elite: Innovation and Clinical Evidence – Rutger-Jan Nuis

  • Case-Based Discussion: Practical Tips for PerQseal® Elite – Mohamed Abdel-Wahab

  • Closing Remarks and Q&A – All Faculty

 



This breakout is supported by Vivasure Medical



Session 1.1

Upstream TAVR Has Arrived, Should Guidelines Follow?

Chair: Nicolas Van Mieghem, Rotterdam, NL and Ole De Backer, Copenhagen, DK

Panel: Sabine Bleiziffer, Bad Oeynhausen, DE; Thomas Modine, Bordeaux, FR; Giuseppe Tarantini, Padua, IT

  • Moderate AS - What’s Next After TAVR UNLOAD – Nicolas Van Mieghem

  • Asymptomatic Severe AS – A Home Run – Nicolas Van Mieghem

  • Pure Aortic Regurgitation – A Legitimate TAVR Target? – Thomas Modine

 




Session 1.2

Live Cases

Chair: Ole De Backer, Copenhagen, DK

Panel: Sabine Bleiziffer, Bad Oeynhausen, DE; Thomas Modine, Bordeaux, FR; Giuseppe Tarantini, Padua, IT

  • Pure Aortic Regurgitation Case – Nicolas Van Mieghem, Erasmus MC, Rotterdam, NL

  • TAVR-in-TAVR Case – Holger Thiele and Mohamed Abdel-Wahab, Leipzig Heart Center, Leipzig, DE

The live case from Leipzig Heart Center is powered by Medinbox®




TAVI Index Procedure: The Value of Valve Optimisation on Long-term Outcomes and Lifetime Management

Symposium

Chair: Rui Teles, Carnaxide, PT

Panel: James Cockburn, Brighton, UK; Birgid Gonska, Bad Nauheim, DE; Vlasis Ninios, Thessaloniki, GR

Case Operator: Won-Keun Kim, University of Giessen & Marburg, Giessen, DE

  • Welcome and Introduction – Rui Teles, Carnaxide, PT

  • TAVI Procedure Optimisation: Lessons From the ACURATE IDE Study – James Cockburn, Brighton, UK

  • Enhancing TAVI Outcomes: Precise Valve Placement and Implantation – Birgid Gonska, Bad Nauheim, DE

  • Implications of Index Procedure Outcomes on Lifetime Patient Management – Vlasis Ninios, Thessaloniki, GR

  • Case in Focus: TAVI for Larger Annuli Patients  – Won-Keun Kim, Giessen, DE

  • Panel Discussion and Q&A – All

 



This symposium is supported by an unrestricted educational grant from Boston Scientific.

*TAVI Index Procedure: The Value of Valve Optimisation on Long-term Outcomes and Lifetime Management has been accredited by the European Board for Accreditation of Continuing Education for Health Professionals (EBAC) for 1 CME point, equating to 1 hour of learning. Physicians may convert EBAC External CME credits to AMA PRA Category 1 Credits™.



Session 1.3

Atrioventricular Valves

Chair: Azeem Latib, New York, US

Panel: Adam Greenbaum, Atlanta, US; David Hildick-Smith, Brighton, UK; Philipp Lurz, Mainz, DE; Thomas Modine, Bordeaux, FR

  • A Plea for Upstream Secondary MR Treatment – Philipp Lurz

  • The Importance of Complete Elimination of TR – Adam Greenbaum

  • How Strongly Do We Need to Recommend Transcatheter LAA Closure – David Hildick-Smith

 




Session 1.4

Live Cases

Chair: Azeem Latib, New York, US

Panel: Adam Greenbaum, Atlanta, US; David Hildick-Smith, Brighton, UK

  • TTVR Case – Philipp Lurz, University Medical Center Mainz, Mainz, DE

  • TTVR Case – Thomas Modine, Bordeaux University Hospital, Bordeaux, FR

The live cases from University Medical Center Mainz and Bordeaux University Hospital are powered by Medinbox®




Day One Close


Day 2 - Complex PCI


Day Two Welcome


Session 2.1

Drug Coated Balloons

Chair: Margaret McEntegart, New York, US

Panel: Joost Daemen, Rotterdam, NL; Roxana Mehran, New York, US; Valeria Paradies, Rotterdam, NL; Giuseppe Tarantini, Padua, IT

  • Overview of the DCB Market / What Is New in Coronary Devices – Margaret McEntegart

  • The Undisputed Indications for DCB – Giuseppe Tarantini

  • How to Interpret a Good DCB Result With Invasive Imaging – Joost Daemen

 




Session 2.2

Live Cases

Chair: Margaret McEntegart, New York, US

Panel: Joost Daemen, Rotterdam, NL; Roxana Mehran, New York, US; Valeria Paradies, Rotterdam, NL; Giuseppe Tarantini, Padua, IT

  • Proximal LAD Imaging Guided – Holger Thiele and Mohamed Abdel-Wahab, Leipzig Heart Center, Leipzig, DE

  • LM Bifurcation DCB Case – David Hildick-Smith, Royal Sussex County Hospital, Brighton, UK

 

The live cases from Leipzig Heart Center and Royal Sussex County Hospital are powered by Medinbox®




Optimising the Therapeutic Management of Women With Aortic Stenosis: Insights and Implications From Emerging Data

Breakout

Chair: Roxana Mehran, New York, US

Panel: Sinjini Biswas, Melbourne, AU; Marta Kaluzna-Oleksy, Poznan, PL; Zainab Dakhil, Baghdad, IQ

  • Pre-procedural Screening and Specific Challenges for Valve Selection in Female Patients – Roxana Mehran

  • Peri- and Post-procedural Considerations for Female Patients – Sinjini Biswas

  • Women Undergoing Aortic Valve Replacement – Marta Kaluzna-Oleksy

  • Asymptomatic AS Patients and the EARLY TAVR Trial – Zainab Dakhil

  • Panel Discussion and Q&A

 



This breakout is in partnership with Women as One.



Session 2.3

Calcium Modification Revisited

Chair: Ajay Kirtane, New York, US

Panel: Azeem Latib, New York, US; Margaret McEntegart, New York, US; Valeria Paradies, Rotterdam, NL; Holger Thiele, Leipzig, DE

  • Latest Science on Atherectomy – Ajay Kirtane

  • Updates on Coronary Lithotripsy – Azeem Latib

  • Use More Invasive Imaging Guidance – Valeria Paradies

 




Session 2.4

Live Cases

Chair: Ajay Kirtane, New York, US

Panel: Azeem Latib, New York, US; Margaret McEntegart, New York, US; Valeria Paradies, Rotterdam, NL; Holger Thiele, Leipzig, DE

  • Atherectomy Case – Joost Daemen and Nicolas Van Mieghem, Erasmus MC, Rotterdam, NL

  • Lithotripsy Case – Amit Hooda and Annapoorna Kini, Mount Sinai, New York, US

 




Day Two Close


Day 3 - Debates & Controversies


Day Three Welcome


Session 3.1

Keynote & Debate

Chair: Ajay Kirtane, New York, US

Panel: Roxana Mehran, New York, US; Holger Thiele, Leipzig, DE; Nicolas Van Mieghem, Rotterdam, NL

Keynote: Michael Gibson, Boston, US

  • The Future of Digital Health / AI and Trials of the Future – Michael Gibson

  • ACC Highlights – Roxana Mehran

 




Session 3.2

Live Cases

Chair: Ajay Kirtane, New York, US

Panel: Mohamed Abdel-Wahab, Leipzig, DE; Philipp Lurz, Mainz, DE; Roxana Mehran, New York, US; Holger Thiele, Leipzig, DE

  • TAVR in Low-Risk Patients Using an Intra-annular Device and a Dedicated Physiology Wire – Nicolas Van Mieghem and Rutger-jan Nuis, Erasmus MC, Rotterdam, NL

  • LAA Case – David Hildick-Smith, Royal Sussex County Hospital, Brighton, UK

 

The live case from Royal Sussex County Hospital is powered by Medinbox®




Session 3.3

Controversies

Chair: Nicolas Van Mieghem, Rotterdam, NL

Panel: Joost Daemen, Rotterdam, NL; Michaela Hell, Mainz, DE; Ajay Kirtane, New York, US; Holger Thiele, Leipzig, DE

  • Is Photon Counting CT a Game Changer? – Michaela Hell

  • Pulmonary Thrombectomy Deserves a Strong Recommendation in the Guidelines – Holger Thiele

  • How Valid Is Quality of Life as a Major Study Endpoint? – Joost Daemen

 




Day Three Close


Day 4 - US Focus

US Focus – Coronary Sessions


Day Four Welcome


Session 4.1

Renal Denervation – Time for Action

Chair: Ajay Kirtane, New York, US

Panel: Jeremy Bock, Arlington, US; Naomi Fisher, Boston, US; Antonio Gutierrez, Durham, US; Matheen Khuddus, Gainesville, US; Eric Secemsky, Boston, US; Raven Voora, Chapel Hill, US

  • Which Patients Benefit From RDN – Naomi Fisher

  • How to Set Up a RDN Programme in 2025 – Jeremy Bock

  • Case Presentation – Eric Secemsky

  • Case Presentation – Antonio Gutierrez

 




Session 4.2

DCBs in Contemporary Practice

Chair: Ajay Kirtane, New York, US

Panel: Suhail Dohad, Los Angeles, US; Kathleen Kearney, Seattle, US; Azeem Latib, New York, US; Margaret McEntegart, New York, US

  • What Are DCBs and Why and How Do I Use Them? – Azeem Latib

  • Case Presentation – Kathleen Kearney

 




Session 4.3

Approaching Calcified Lesions in 2025

Chair: Ajay Kirtane, New York, US

Panel: Suhail Dohad, Los Angeles, US; Kathleen Kearney, Seattle, US; Margaret McEntegart , New York, US

  • What’s Our Strategy? – Margaret McEntegart

  • What Role Does Imaging Play? – Suhail Dohad

 




Session 4.4

Should Acute PE Intervention Be Performed Routinely by ICs?

Chair: Jay Giri, Philadelphia, US

Panel: Jay Mathews, Bradenton, US; Sahil Parikh, New York, US; Sonal Pruthi, New York, US; Sanjum Sethi, New York, US

  • Should Acute PE intervention be performed routinely by ICs? – Sahil Parikh

  • How to Set Up an Acute PE Program – Jay Mathews

 




US Focus – Structural Sessions

5:00 PM - 5:40 PM (CEST)

Session 4.5

Aortic Session

Chair: Azeem Latib, New York, US

Panel: Sebastian Iturra, Minneapolis, US; Amar Krishnaswamy, Cleveland, US, Susheel Kodali, New York, US; Andrea Scotti, New York, US; Nicolas Van Mieghem, Rotterdam, NL

  • TAVR in Younger Patients – Where Do We Stand? – Andrea Scotti

  • Case-In-A-Box With Discussion – TAVR in TAVR / TAVR Explant – Sebastian Iturra

  • The Future – Amar Krishnaswamy

 



5:40 PM - 6:20 PM (CEST)

Session 4.6

Mitral Session

Chair: Azeem Latib, New York, US

Panel: Anita Asgar Chicago, US; Manaf Assafin, New York, US; Neil Fam, Toronto, CA; Susheel Kodali, New York, US; Scott Lim, Charlottesville, US; Nicolas Van Mieghem, Rotterdam, NL

  • Contemporary Mitral Valve Intervention in 2025 – Anita Asgar

  • Case-In-A-Box With Discussion – Emerging Technology – Manaf Assafin

  • The Future – Scott Lim

 



6:20 PM - 7:00 PM (CEST)

Session 4.7

Tricuspid Session

Chair: Azeem Latib, New York, US

Panel: Anita Asgar Chicago, US; Neil Fam, Toronto, CA; Edwin Ho, New York, US; Susheel Kodali, New York, US; Nicolas Van Mieghem, Rotterdam, NL

  • Contemporary Tricuspid Valve Intervention in 2025 – Edwin Ho

  • Case-in-a-box With Discussion – Emerging Technology – Neil Fam

  • The Future – Susheel Kodali

 



7:05 PM - 7:50 PM (CEST)

Management of Degenerative MR With TEER: An Evidence-based Guide

Symposium

Chair: Tarun Chakravarty, Los Angeles, US

Panel: Firas Zahr, Portland, US; Tom Cahill, Oxford, UK

  • Welcome and Introduction – Tarun Chakravarty

  • Transcatheter Repair: Selection in Degenerative MR – Tarun Chakravarty

  • Making Evidence-based Decisions in TEER – Insights From Recent Clinical Data – Firas Zahr

  • Technical Considerations for TEER in DMR Patients – Tom Cahill

  • Panel Discussion and Q&A – All

 



This symposium is supported by an unrestricted educational grant from Edwards Lifesciences.

*This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of PeerPoint Medical Education Institute and Radcliffe Medical Education. PeerPoint Medical Education Institute is accredited by the ACCME to provide continuing medical education for physicians.

PeerPoint Medical Education Institute designates the live and enduring format for this educational activity for a maximum of 0.75 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Live activity date: April 12, 2025 Enduring activity dates: April 30, 2025 – April 30, 2026


8:00 PM - 8:55 PM (CEST)

Session 4.8

Chair: Nicolas Van Mieghem, Rotterdam, NL and Azeem Latib, New York, US

  • ICE-Guided LAAO Case – Karim Al Azizi and Sibi Thomas, Baylor Scott & White - The Heart Hospital Plano, Plano, US



8:55 PM - 9:00 PM (CEST)

Day Four Close


Course Leadership

Nicolas Van Mieghem

Nicolas Van Mieghem
Course Director
Thoraxcenter, Erasmus MC, Rotterdam, NL

more info

David Hildick-Smith

David Hildick-Smith
Course co-director
Sussex Cardiac Centre, Brighton and Sussex University Hospitals, Brighton, UK

more info

Roxana Mehran

Roxana Mehran
Course co-director
The Mount Sinai Hospital, New York, US

more info

Holger Thiele

Holger Thiele
Course co-director
Leipzig Heart Hospital, Leipzig, DE

more info

Ajay Kirtane

Ajay Kirtane
Course co-director
Columbia University Medical Center and New York-Presbyterian Hospital, New York, US

more info

Azeem Latib

Azeem Latib
Course co-director
Montefiore Medical Center, New York, US

more info

Faculty

Prof Mohamed Abdel-Wahab
Mohamed Abdel-Wahab

Leipzig Heart Center, Leipzig, DE

 Anita Asgar
Anita Asgar

Northwestern University, Chicago, US

 Sinjini Biswas
Sinjini Biswas

Royal Melbourne Hospital, Melbourne, AU

 Sabine Bleiziffer
Sabine Bleiziffer

Heart and Diabetes Center NRW, Bad Oeynhausen, DE

 James Cockburn
James Cockburn

Royal Sussex County Hospital, Brighton, UK

Dr Joost Daemen
Joost Daemen

Thoraxcenter, Erasmus MC, Rotterdam, NL

 Zainab Dakhil
Zainab Dakhil

University of Baghdad, Baghdad, IQ

 Ole De Backer
Ole De Backer

Rigshospitalet, Copenhagen, DK

 Michael Gibson
Michael Gibson

Harvard Medical School, Boston, US

 Birgid Gonska
Birgid Gonska

Kerckhoff Heart Center, Bad Nauheim, DE

 Adam Greenbaum
Adam Greenbaum

Emory University, Atlanta, US

 Michaela Hell
Michaela Hell

University Medical Center Mainz, Mainz, DE

 Amit Hooda
Amit Hooda

Mont Sinai Hospital, New York, US

 Marta Kaluzna-Oleksy
Marta Kaluzna-Oleksy

University of Medical Sciences, Poznan, PL

 Won-Keun Kim
Won-Keun Kim

University of Giessen & Marburg, Giessen, DE

Dr Philipp Lurz
Philipp Lurz

University Medical Center Mainz, Mainz, DE

Dr Margaret McEntegart
Margaret McEntegart

Columbia University Medical Center and New York-Presbyterian Hospital, New York, US

 Thomas Modine
Thomas Modine

Bordeaux University Hospital, Bordeaux, FR

 Vlasis Ninios
Vlasis Ninios

European Interbalkan Medical Center, Thessaloniki, GR

 Rutger-jan Nuis
Rutger-jan Nuis

Erasmus MC, Rotterdam, NL

 Valeria Paradies
Valeria Paradies

Maasstad Hospital, Rotterdam, NL

Prof Giuseppe Tarantini
Giuseppe Tarantini

University Hospital of Padova, Padova, IT

 Rui Teles
Rui Teles

Hospital de Santa Cruz, Carnaxide, PT

Learning Objectives

Day 1 - Structural Heart Disease

  • Assess TAVR's role in asymptomatic and moderate AS for future guidelines
  • Review new options for treating pure aortic regurgitation and mitral/tricuspid regurgitation
  • Explore emerging technologies in structural heart disease

Day 2 - Complex PCI

  • Discuss key uses and outcomes of Drug-Coated Balloons (DCBs) and new coronary devices
  • Review calcium modification techniques and the value of invasive imaging

Day 3 - Debates & Controversies

  • Explore how AI is shaping interventional cardiology
  • Debate pulmonary thrombectomy, MINOCA treatment, and ACC highlights

Day 4 - US Focus

  • Examine Drug-Coated Balloons (DCBs) in coronary procedures
  • Review advancements in Renal Denervation for hypertension
  • Understand strategies for managing calcified lesions and imaging
  • Assess the need for routine acute PE intervention
  • Explore contemporary mitral and tricuspid valve interventions and latest technologies

(Please note these learning objectives are subject to change)

Target Audience

  • Interventional Cardiologists
  • Surgeons with an interest in transcatheter treatment strategies for coronary and structural heart disease
  • Interventional Cardiology Nurses

Headline Educational Partner

Educational Partners

Supporting Partners

Live Broadcast Partner

The live cases from Leipzig Heart Center; University Medical Center Mainz; Bordeaux University Hospital and Royal Sussex County Hospital are powered by Medinbox®

Headline Educational Partner

Educational Partners

Supporting Partners

If you’re interested in becoming an educational partner at TIO, please contact sales@radcliffe-group.com

Official Journal

Interventional Cardiology: Reviews, Research, Resources (ICR³) is an international, English language, peer-reviewed journal that publishes articles continuously on ICRjournal.com. It aims to assist time-pressured physicians to stay abreast of key advances and opinions in interventional cardiology.

Led by Editor-in-Chief Peter O'Kane, along with Deputy Editors and an editorial board of world-renowned physicians, the journal publishes peer-reviewed articles that aim to provide timely updates on the most pertinent issues in the field.

View the 2024 volume of ICR3

About Radcliffe Cardiology

We are Radcliffe, a knowledge network for the cardiovascular community

We’re here to bring cardiovascular knowledge, insight and innovation to life for clinicians around the world, using our communications and creative expertise, our platforms and connections across the community to help transform theory into practice faster and more effectively.

We bring medical knowledge to life

From great science writing and smart journal editing, the curation of evidence based and peer-reviewed content, to engaging new formats that cut through the noise, we believe that communication is at the heart of great healthcare.

Our work is underpinned by 3 core principles:

  • We build on the best science
  • We work hands-on with our community
  • We bring fresh thinking


Our promise is that we’ll equip you with the latest knowledge and skills you need, to do the best for your patients.

For more information on Radcliffe Cardiology, please visit www.radcliffecardiology.com